Category: News

Men's Health Monday: Health Screenings for Men

June is Men's Health Awareness Month. Learn about the top 3 types of cancer affecting men.

Breast-Fed Children at Lower Risk of Leukemia

A new study suggests what scientists have long suspected about the protective effects of breast milk against one of the leading killers of children.

Evidence Suggesting that Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors

The anaplastic lymphoma kinase ALK is chromosomally rearranged in a subset of certain cancers, including 2-7% non-small cell lung cancers (NSCLC) and ~70% of anaplastic large cell lymphomas (ALCL). The ALK kinase inhibitors crizotinib and ceritinib are...

Minor changes in expression of the mismatch repair protein MSH2 exert a major impact on glioblastoma response to temozolomide

Glioblastoma (GBM) is often treated with the cytotoxic drug temozolomide (TMZ) but the disease inevitably recurs in a drug-resistant form after initial treatment. Here we report that in GBM cells even a modest decrease in the mismatch repair (MMR) comp...

Minor Decreases in MSH2 Mediate Chemoresistance

Glioblastoma (GBM) is often treated with the cytotoxic drug temozolomide, but the disease inevitably recurs in a drug-resistant form after initial treatment. Here, we report that in GBM cells, even a modest decrease in the mismatch repair (MMR) compone...