In acute promyelocytic leukemia (APL), all-trans-retinoic acid (ATRA) treatment induces granulocytic maturation and complete remission of leukemia. MicroRNA are known to be critical players in the formation of the leukemic phenotype. In this study, we ...

Tumors cells can escape cytotoxic CD8+ T cells by preventing MHC I display of tumor antigens. It is unknown how tumors evade CD4+ T-cell responses, but because many tumor cells lack MHC II expression, novel mechanisms would be required. We have investi...

Tumors cells can escape cytotoxic CD8+ T cells by preventing MHC I display of tumor antigens. It is unknown how tumors evade CD4+ T cell responses, but since many tumor cells lack MHC II expression, novel mechanisms would be required. We have investiga...

Learn about the top three types of cancer affecting men - prostate, testicular and colorectal - and how to stay one step ahead.

June is Men's Health Awareness Month. Learn about the top 3 types of cancer affecting men.