Short-term starvation or fasting can augment cancer treatment efficacy and can be effective in delaying cancer progression in the absence of chemotherapy, but the underlying molecular mechanisms of action remain elusive. Here, we describe the role of ...

Acute myeloid leukemia is a heterogeneous disease in which a variety of distinct genetic alterations occur. Recent studies to identify the leukemia stem-like cells (LSCs) have also indicated heterogeneity of these cells. Based on mathematical modeling ...

Acute myeloid leukemia (AML) is a heterogeneous disease in which a variety of distinct genetic alterations might occur. Recent attempts to identify the leukemia stem-like cells (LSC) have also indicated heterogeneity of these cells. On the basis of ma...

Drinking coffee is associated with a slightly reduced risk for skin cancer, a new study has found.

Genetic mouse studies suggest that the NF-κB pathway regulator NEMO (also known as IKKγ) controls chronic inflammation and carcinogenesis in the liver. However the molecular mechanisms explaining the function of NEMO are not well defined. Here we rep...