Glioma-initiating cells (GICs) have stem-like cell properties thought to be sufficient for recurrence, progression and drug resistance in glioblastomas. In the present study, we defined miR-340 as a differentially expressed microRNA (miRNA) in human GI...

The mobilization of bone marrow-derived cells (BMDCs) to distant tissues prior to the arrival of disseminated tumor cells has been shown preclinically to facilitate metastasis through the establishment of metastatic niches. Primary tumor hypoxia has be...

The mobilization of bone marrow–derived cells (BMDC) to distant tissues before the arrival of disseminated tumor cells has been shown preclinically to facilitate metastasis through the establishment of metastatic niches. Primary tumor hypoxia has be...

Cigarette smoking is a major risk factor in the development of non-small cell lung cancer (NSCLC), which accounts for 80% of all lung cancers. Nicotine, the major addictive component of tobacco smoke, can induce proliferation, invasion and epithelial-m...

Short-term starvation or fasting can augment cancer treatment efficacy, but can also be effective in delaying cancer progression in the absence of chemotherapy. However, the underlying molecular mechanism remains elusive. REV1, a specialized DNA polyme...