Category: News

A p16 Missense SNP Underlying ALL Risk

Genome-wide association studies (GWAS) have identified SNPs in six genes that are associated with childhood acute lymphoblastic leukemia (ALL). A lead SNP was found to occur on chromosome 9p21.3, a region that is deleted in 30% of childhood ALLs, sugge...

A Grim Breast Cancer Milestone for Black Women

For the first time the incidence of breast cancer among black women is equal to that of white women, the American Cancer Society reports.

A preclinical model of malignant peripheral nerve sheath tumor-like melanoma is characterized by infiltrating mast cells

Human melanomas show considerable variations in genetic changes, cell morphology and in microenvironmental composition. Genetically engineered mice have successfully been used to model the impact of genomic aberrations involved in melanoma pathogenesis...

Modeling spontaneous metastasis following surgery: an in vivo-in silico approach

Rapid improvements in the detection and tracking of early-stage tumor progression aim to guide decisions regarding cancer treatments as well as predict metastatic recurrence in patients following surgery. Mathematical models may have the potential to f...

Vitamin D and Calcium Fail to Reduce Colon Tumor Risk

A randomized trial has found that neither calcium nor vitamin D was effective in reducing the risk of tumors of the colon or rectum.