Category: News

Why the Five-Year Survival Rate for Cancer Matters

When cancer survivors hit the five-year mark, it’s a milestone. Learn why this survival rate matters and what it really means.

Living With Cancer: The Lure of Alternative Remedies

Sick people need all sorts of strategies, alongside medical ones, to deal with disease.

Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes

The anticancer properties of cruciferous vegetables are well known and attributed to an abundance of isothiocyanates (ITCs) such as benzyl ITC (BITC) and phenethyl ITC (PEITC). While many potential targets of ITCs have been proposed, a full understandi...

Nitric Oxide Is an Epigenetic Regulator of Gene Expression

Altered nitric oxide (•NO) metabolism underlies cancer pathology, but mechanisms explaining many •NO-associated phenotypes remain unclear. We have found that cellular exposure to •NO changes histone posttranslational modifications (PTM) by direct...

uPAR Promotes Skin Tumor Formation

The urokinase-type plasminogen activator receptor (uPAR) has a well-established role in cancer progression, but it has been little studied at earlier stages of cancer initiation. Here, we show that uPAR deficiency in the mouse dramatically reduces susc...