Global changes in gene expression accompany the development of cancer. Thus, inherited variants in miRNA-binding sites are likely candidates for conferring inherited susceptibility. Using an in silico approach, we compiled a comprehensive list of SNPs...

Global changes in gene expression accompany the development of cancer. Thus, inherited variants in microRNA binding sites are likely candidates for conferring inherited susceptibility. Using an in-silico approach, we compiled a comprehensive list of SN...

BRCA1 expression is lost frequently in breast cancers where it promotes malignant development. In the present study, we performed a global expression analysis of breast cancer cells where the tumor suppressor candidate gene TUSC4 was silenced to gain i...

Estrogen receptor α (ER)-positive breast cancers initially respond to antiestrogens but eventually become estrogen-independent and recur. ER+ breast cancer cells resistant to long-term estrogen deprivation (LTED) exhibit hormone-independent ER transcr...

Estrogen receptor (ER) α–positive breast cancers initially respond to antiestrogens but eventually become estrogen independent and recur. ER+ breast cancer cells resistant to long-term estrogen deprivation (LTED) exhibit hormone-independent ER tran...