Category: News

Proton Therapy: Five Signs Cancer Care Is Rapidly Evolving

Welcome to the future of radiation therapy.

Akt signaling is sustained by a CD44 splice isoform-mediated positive feedback loop

Tumor cells nearly invariably evolve sustained PI3K/Akt signaling as an effective means to circumvent apoptosis and maintain survival. However, for those tumor cells that do not acquire PI3K/Akt mutations to achieve this end the underlying mechanisms h...

VHL inactivation in precancerous kidney cells induces an inflammatory response via ER stress-activated IRE1{alpha} signaling

Mutations and epigenetic inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) are major causes of clear-cell renal cell carcinoma (ccRCC) that may originate from chronic inflammation. However, the role of VHL loss-of-function in the develo...

Water Concentration Analysis of the Surgical Margin—Response

Water Concentration Analysis of the Surgical Margin—Letter