Category: News

Focus on Cancer RSS Feed 2015-03-16 16:14:00

March is Colorectal Cancer Awareness Month. To learn more about screening, symptoms, treatments and the latest research, we’re teaming up with 6ABC for a live, streaming web chat at 6abc.com/pennmedicine. Colorectal Cancer - Did you know?

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RSpo2 enhances canonical Wnt signaling to confer stemness-associated traits to susceptible pancreatic cancer cells

Cancer stem cells (CSCs) present a formidable clinical challenge by escaping therapeutic intervention and seeding tumors through processes that remain incompletely understood. Here, we describe small subpopulations of pancreatic cancer cells with high ...

Susceptibility to RSPO2 Defines Pancreatic Cancer Stem Cells

Cancer stem cells (CSC) present a formidable clinical challenge by escaping therapeutic intervention and seeding tumors through processes that remain incompletely understood. Here, we describe small subpopulations of pancreatic cancer cells with high ...

Loss of VEGF Induces Melanoma Niche Morphogenesis

The basis for resistance to VEGF inhibition is not fully understood despite its clinical importance. In this study, we examined the adaptive response to VEGF-A inhibition by a loss-of-function analysis using plasmid-based shRNA. Tumor xenografts that ...

Induction of vasculogenic mimicry overrides VEGF-A silencing and enriches stem-like cancer cells in melanoma

The basis for resistance to VEGF inhibition is not fully understood despite its clinical importance. In this study, we examined the adaptive response to VEGF-A inhibition by a loss-of-function analysis using plasmid-based shRNA. Tumor xenografts that i...