Category: News

Breast-Feeding May Cut Breast Cancer Recurrence Risk

In mothers who later develop breast cancer, having breast-fed a child may reduce the risk of cancer recurrence.

KRAS Status Predicts Sensitivity to Decitabine in Ovarian Cancer

Decitabine, a cancer therapeutic that inhibits DNA methylation, produces variable antitumor response rates in patients with solid tumors that might be leveraged clinically with identification of a predictive biomarker. In this study, we profiled the re...

KRAS genomic status predicts sensitivity to decitabine in an extended assay in ovarian cancer cell lines

Decitabine, a cancer therapeutic that inhibits DNA methylation, has elicited moderate to low response rates in patients with solid tumors. Despite efforts to identify responders based on DNA methylation, a marker for decitabine activity has yet to be d...

GM-CSF and Modulation of PDAC Microenvironment

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic malignancies. PDAC builds a tumor microenvironment that plays critical roles in tumor progression and metastasis. However, the relationship between chemotherapy and modulatio...

Chemotherapy-derived inflammatory responses accelerate the formation of immunosuppressive myeloid cells in the tissue microenvironment of human pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic malignancies. PDAC builds a tumor microenvironment that plays critical roles in tumor progression and metastasis. However, the relationship between chemotherapy and modulatio...